Larger than Life(1977)

Endriade's wife died in a tragic car accident 10 years ago. The scientist now lives in a secret laboratory high in the mountains under close military supervision. He and a few other scientists have created an artificial super-brain that knows everything. Outwardly, this higher knowledge looks like his long-deceased wife, but in addition to its appearance, it also received her personality, which rebels against its creators and begins killing them.